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Index > Protein center > Adam2(Gene name) > Rat
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  • Adam2 (Gene name),
  • Disintegrin and metalloproteinase domain-containing protein 2 (Protein name ),  ADAM2_RAT from NCBI database.
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  • Gene name:
    Adam2(Ftnb);
    Protein name:
    Disintegrin and metalloproteinase domain-containing protein 2(ADAM 2);
    Alternative:
    PH-30(PH30);Fertilin subunit beta;PH30-beta;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Heterodimer with ADAM1/fertilin subunit alpha.
    Function:
    Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    737
    Sequence:
    50:
    MWLLLLLLSG | LSRLGGLSEP | QTEGTREKLH | VQVTVPEKIR | SITSEGYETQ | 
    100:
    VTYSLKIEGK | TYILNLMQKA | FLPPNFRVYS | YDSTGIMRPL | EQKFQNICYF | 
    150:
    QGYIEGYPNS | MVIVSTCTGL | RGVLQFGNVS | YGIEPLESSS | GFEHVIYQVE | 
    200:
    PKKGDTLLYA | EKDMDLRDPQ | YKIRSIKPQR | TVSHYLEIHI | VVEKQMFEHI | 
    250:
    GADTAVVTQK | IFQLIGLTNA | IFAPFNLTVI | LSSLEFWMDE | NKISTTGDAN | 
    300:
    KLLYRFLKWK | QSYLVLRPHD | MAFLLVYRDT | TDYVGATYQG | KMCDKNYAGG | 
    350:
    VALHPKAVTL | ESLAIILVQL | LSLSMGVAYD | DVNTCQCGVP | ICVMNPEALH | 
    400:
    SSGVRSFSNC | SMEDFSKFIV | SQSSHCLQNQ | PHLQPSYKMA | VCGNGELEEG | 
    450:
    EVCDCGQEGC | DDKPPPCCNP | TTCQLSEGST | CSTGSCCDAS | CNLKAKGELC | 
    500:
    RPANQECDVT | EYCNGTSEVC | EEDFFVQDGH | PCAEQKWICI | NGTCQSGAQQ | 
    550:
    CRDLFGTDAD | YGTKECYSEL | NSKSDISGSC | GITPTGYKDC | APNDRMCGKL | 
    600:
    ICIYQSEDIL | KMRSAIVIYA | NISGQICISL | EYPPGHKESK | KMCVRDGTVC | 
    650:
    GSGKVCLNQE | CVEDTFLNYD | CTPEKCNHHG | VCNNKKHCHC | EPTYLPPDCK | 
    700:
    NTEDTWPGGS | VDSGNQQRAE | SIPARSYVAS | AYRSKSARWP | FFLIIPFYVV | 
    737:
    ILVLIGMLVK | VYSQRKKWRM | DDFSSEEQFE | SESESKD
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat ADAM 2
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    CLIA Kit for Rat ADAM 2
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    CLIA Kit for Rat ADAM 2
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    Packing:
    96T
    CLIA Kit for Rat ADAM 2
    Cat.:
    U14287m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat ADAM 2
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    U14287r
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    Polyclonal Antibody for Rat ADAM 2
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    P14287Rb-m
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    40ug/0.2ml
    Polyclonal Antibody for Rat ADAM 2
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    P14287Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat ADAM 2
    Polyclonal Antibody for Rat ADAM 2
    Polyclonal Antibody for Rat ADAM 2
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    P14287Rb-h
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat ADAM 2
    Monoclonal Antibody for Rat ADAM 2
    Monoclonal Antibody for Rat ADAM 2
    Monoclonal Antibody for Rat ADAM 2
    Monoclonal Antibody for Rat ADAM 2
    Protein for Rat ADAM 2
    Protein for Rat ADAM 2
    Protein for Rat ADAM 2
    Protein for Rat ADAM 2
    Protein for Rat ADAM 2

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    References
    1. 1.
      "Cloning and sequence analysis of rat fertilin alpha and beta -developmental expression, processing and immunolocalization."
      McLaughlin E.A. , Frayne J. , Barker H.L. , Jury J.A. , Jones R. , Ford W.C.L. , Hall L.
      Mol. Hum. Reprod.3:801-809(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Testis.
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